Original Research Paper

Genetic Disorders That Cause Stillbirth And Abortion In Cattle

Abstract :

Genetic disorder is an illness caused by inborn abnormalities in gene or chromosomes, which are quite rare. It causes abortion and still birth. The word abortion is usually used to define the termination of a pregnancy, and still birth occurs anytime a calf dies from 260 days of gestation up until 24 hours post calving. Genetic disorders in cattle are mostly caused by autosomal recessively inherited gene. These autosomal recessively inherited genes are formed due to deletion or insertion of mutant genes. The genetic diseases in dairy and beef cattle are tissue specific viz; Skeletal, Central Nervous System and Blood. Genetic disorders that cause abortion and still birth in cattle includes skeletal disorders such as: Achondroplasia, Mulu Foot (syndactylism), Complex Verteal Malformation, Arachnomelia, Osteogenesis Imperfecta, Arthrogryposis Multiplex and Brachyspina syndrome; central nervous system disorders such as: spinal dysmyelination and spinal muscular atrophy; blood tissue disorders of, Bovine Leukocyte Adhesion Deficiency. It causes loss of calf, lower fertility of the dam at the next eeding, longer calving to conception interval, and a tendency for milk production to be decreased. Therefore, in order to reduce this economic lose the DNA testing is currently available for some of the genetic disease; however, it is necessary to develop it for all the genetic diseases so that eeding sires can be effectively screened for undesirable alleles and culled to avoid further propagation in eeding population.

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