ijmedicine

INTERNATIONAL JOURNAL OF ADVANCED MEDICINE (IJAM)

ISSN (O) : 2663 - 046X

A CrossRef Indexed Journal

DOI : 10.34300/26630451

ISSN (P) : 2663 - 0451

IC VALUE : 89.03 (2020)

International Journal of Advanced Medicine (IJAM)
Original Research Paper

Congenital Cmv Meningitis In An Immunocompetant Infant With Hirschsprung's Disease - A Case Report

Dr. Vaishnavi Bhagat, Dr. Rajesh Kulkarni, Dr. Aarti Kinikar

Abstract :

Cytomegalovirus (CMV) is a common perinatal infection that tends to follow a silent course and only 515% of CMV-infected infants are symptomatic at birth, with signs and symptoms characterized by the involvement of multiple organs, particularly the reticuloendothelial and central nervous systems. (1,2)Gastrointestinal involvement is considered rare, and may vary depending on the location and extent of the disease, with different manifestations.(1,2,3,4,5,6)Few studies have also reported etiological association of Hirschsprungs disease with congenital CMV infection, due to damage of myentric plexus by the virus causing aganglinosis. (1,5,6) We report a case of coexistence of congenital CMV infection in the form of CMV meningitis with Hirschsprungs disease in a male infant born at 39 weeks gestation. The serologic data and DNA PCR report suggested a CMV infection of CNS and the pathologic findings of resected bowel specimens showed hypoganglionosis. Our report shows congenital CMV infection may be etiologically associated with Hirschsprung disease.

Keywords :

Congenital CMV infection   Hirschprung’s disease   immunocompetent infant  

Cite This Article:

CONGENITAL CMV MENINGITIS IN AN IMMUNOCOMPETANT INFANT WITH HIRSCHSPRUNG'S DISEASE - A CASE REPORT, Dr. Vaishnavi Bhagat, Dr. Rajesh Kulkarni, Dr. Aarti Kinikar, INTERNATIONAL JOURNAL OF ADVANCED MEDICINE : Volume-6 | Issue-2 | March-2022

References :


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