Research Paper

Role Of Peak Systolic Velocity Of Inferior Thyroid Artery In Differentiation Of Graves Disease And Hashimotos Thyroiditis In Thyrotoxicosis.

Abstract :

AIM: To evaluate the role of inferior thyroid artery (ITA) peak systolic velocity (PSV) assessed by color Doppler in the differential diagnosis of thyrotoxicosis.METHOD: Forty three patients with thyrotoxicosis were included in our study. A detailed clinical history was taken from all patients followed by physical examination and thyroid function tests and thyroid autoantibody levels. The thyroid glands were evaluated by gray scale ultrasound for volume and echotexture. Doppler ultrasonography was performed and PSV of both inferior thyroid arteries was assessed. FNAC was done in all patients to confirm the diagnoses. The patients were divided into two groups: 23 cases with Graves disease and 20 cases with Hashimotos thyroiditis. All patients had suppressed thyrotropin. The diagnosis was further supported by the clinical picture and follow up of the patients.RESULTS: Peak systolic velocity of the inferior thyroid arteries were significantly higher in patients with Graves disease than in patients with Hashimotos thyroiditis (P = 0.001). Doppler ultrasound parameters demonstrated a sensitivity of 86.9% and a specificity of 85.0% in the differential diagnosis of thyrotoxicosis.CONCLUSION: Color Doppler assessment of inferior thyroid artery can be helpful in the differential diagnosis of thyrotoxicosis, especially when there is a contraindication or lack of availability of thyroid scintigraphy.

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