Original Research Paper

Antibacterial Agents: Bacteriostatic And Bactericidal

Abstract :

Bacteria are microorganisms which called prokaryotic that have a few micrometres in length. Bacteria are live in thesoil, water, acidic hot springs, radioactive waste, and the deep portions of earths crust and among microorganismbacteria are the rst life forms appeared on the earth. Penicillins block a bacterial enzyme called transpeptidaseenzyme which is used for the secretion of bacterial cell wall. Probenecid accelerates the amount of penicillins in blood serum levels bypreventing the excretion of penicillin through kidneys. Ceftriaxone is not given in hyperbilirubinemic neonates because ceftriaxone displacesbilirubin from albumin, and enhancing the free bilirubin accumulations and accelerates the risk of jaundice in neonates. Ceftriaxone has theability to react with calcium-containing solution and also have the ability to form precipitate in lungs and kidneys of infants less than twentyeight days old and this side effect may be life-threatening; so ceftriaxone is given with products which containing calcium such as ringerlactate in infants less than twenty days old and all population. Vancomycin is given for the management of severe infections caused byvulnerable strains of methicillin-resistant (beta-lactam-resistant) staphylococci.

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