Research Paper

Spectrum Of Bacterial Pathogens And Their Antibiotics Sensitivity Patterns In The Sputum Of Patients With Acute Exacerbation Of Chronic Obstructive Pulmonary Disease.

Abstract :

Aim-The aim of our study is to isolate bacterial pathogens in sputum culture of patients with acute exacerbation of COPD and sensitivity pattern of these pathogens.Materials and Methods-The sample includes a total of 60 AECOPD patients with positive sputum culture was taken in to the study after satisfying all the criteria.Two sputum samples were collected from each patient, one at the time of admission and the other early in the morning. Routine hematological investigations and chest x-ray were done on the day of presentation. The data was entered into Microsoft excel spreadsheet 2007 and analysed using IBM SPSS Version 16.0. Basic descriptive statistics were used to summarise the data.Results-The age group of the patients studied ranged from 45 to 82 years, the most common age group being 56 to 65 years (45%), followed by 66 to 75 years (28%). They are 100% susceptible to amino glycosides (100%) and Piperacillin-Tazobactum (100%).The organisms showed very high susceptibility to 3rd generation Cephalosporins (100%), ciprofloxacin (100%), Amikacin (100%) and Azithromycin (100%).Conclusion-The common organisms causing AECOPD in our study were gram negative organisms. Organisms isolated were Klebsiella followed by Pseudomonas aeruginosa. They were sensitive to aminoglycosides like gentamycin and Amikacin.

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