Research Paper

Comparitive Evaluation Of Haematological Profile In Patients With Alcoholic Liver Disease And Non Alcoholic Fatty Liver Disease With Special Emphasis On Platelet Indices

Abstract :

The study was conducted as a randomized , cross sectional analysis . It consisted of total 150 subjects divided into 3 groups Group A(alcoholics), Group B(non alcoholics) and Group C(controls), each group having 50 subjects.The samples were assayed in complete blood count differential mode in the sysmex XN1000 haematology analyserWe compared RBC indices and platelet indices between the 3 group. Hb, MCV and RDW were statistically significant in Group A and Group B than in Group C, more so in Group A than in Group C. Platelet count and plate crit were statistically lower in Group A and Group B than in Group C, more so in Group A than in Group C. We concluded that along with RBC indices, platelet indices can be used for the non invasive assessment of degree of fiosis in ALD and NAFLD patients thus decreasing the need of liver biopsy for the same.

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