Research Paper

Effect Of Fasting And Postprandial Condition On Left Atrial Electromechanical Delay In Healthy Non Diabetic Subjects

Abstract :

Background: atrial electromechanical delay (AEMD), which is defined as the time interval between the atrial electrical depolarization and the initiation or peak of atrial mechanical contraction, is associated with atrial remodeling that finally leads to atrial fiillation (AF).Objective: to assess the effect of fasting and postprandial condition on intra-atrial electromechanical coupling in healthy non-diabetic subjectsPatients and methods: 55 subjects were enrolled in this descriptive observational cross sectional study, (mean age was 33.277.49 years, 33 males), all patients were assessed by thorough history taking, clinical examination, 12 lead surface ECG, ECG gated Echocardiography with measurement of atrial electromechanical coupling (PA), left atrial intra-AEMD over a period of 1 year from July 2017 to July 2018 in Mansoura specialized medical hospitalResults: it was found that PA lateral (50.988.07 vs. 50.387.47 ms, p 0.026), PA Septal (34.876.33 vs. 34.166.32 ms, p 0.003) and, left intra-AEMD (PA lateralPA Septal) (16.727.34 vs. 16.216.57 ms, p 0.01), values were higher in post prandial condition than in fasting state Conclusion: Determining electromechanical events including the atrial conduction time with transthoracic echocardiography is a simple, noninvasive method to be assessed. PA lateral, PA septal and left atrium EMD are prolonged in postprandial condition than during fasting

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