Research Paper

High Sensitivity C-reactive Proteins In Chronic Obstructive Pulmonary Disease And Asthma: A Prospective Study In North India

Abstract :

Introduction: High sensitivity C-reactive protein (hs-CRP) is an acute phase reactant with well documented sensitivity that is commonly used to diagnose infections and inflammatory conditions like COPD and Asthma. Aim:The objective is to study the plasma hs-CRP levels in patients of COPD and Asthma. Material and Methods: this is a prospective study for a period of one year from nov. 2017-oct. 2018 conducted at GMC, Jammu which is a tertiary care centre. In our study, out of 100 patients who were studied, 50 were male (50%) and 50 were females (50%) with ratio of male: female was 1:1. Results: Thirty (30%) patients were asthmatics and seventy (70%) patients had COPD, with asthma to COPD ratio of 1:2.3. Conclusion: High sensitivity C-reactive protein (CRP), which is an inflammatory marker, in the present study had a strong association with COPD and asthma both in males and females with interaction P-values in case of male asthmatics (0.003), female asthmatics (0.01), COPD males (0.001) and COPD females (0.001).

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