ijmedicine

INTERNATIONAL JOURNAL OF ADVANCED MEDICINE (IJAM)

ISSN (O) : 2663 - 046X

A CrossRef Indexed Journal

DOI : 10.34300/26630451

ISSN (P) : 2663 - 0451

IC VALUE : 89.03 (2020)

International Journal of Advanced Medicine (IJAM)
Original Research Paper

Acute Portal Vein, Superior Mesenteric Vein And Splenic Vein Thrombosis Secondary To Jak2 V617 Mutation- A Case Report

Dr. Rosly R Jacob, Dr. Anilkumar Ashokan, Dr. Harikrishnan Somasekran, Dr. Abhishek Sasidharan, Dr. Sachin Chandran, Dr. Venkatesh Mony Chandry

Abstract :

Portal vein thrombosis (PVT) is a rare finding which usually occurs in association with local factors such as cirrhosis, malignancy, pancreatitis, intraabdominal infections or systemic hypercoagulable states. It may present acutely as abdominal pain, ascites, fever or exist in a chronic state which is generally asymptomatic and an incidental finding. With advancement in Imaging and laboratory studies, PVT cases are diagnosed more frequently along with its predisposing factors. The invention of JAK2 mutation and its addition to the WHO criteria for Myeloproliferative neoplasm (MPN) diagnosis, has increased the number of MPN cases which were previously labelled idiopathic. We present a case of 54 year old female diagnosed with unprovoked PVT with bowel ischemia and JAK 2 mutation positive, managed surgically and with long term anticoagulation.

Keywords :

portal vein thrombosis   JAK 2 mutation   myeloproliferative neoplasm  

Cite This Article:

ACUTE PORTAL VEIN, SUPERIOR MESENTERIC VEIN AND SPLENIC VEIN THROMBOSIS SECONDARY TO JAK2 V617 MUTATION- A CASE REPORT, Dr. Rosly R Jacob, Dr. Anilkumar Ashokan, Dr. Harikrishnan Somasekran, Dr. Abhishek Sasidharan, Dr. Sachin Chandran, Dr. Venkatesh Mony Chandry, INTERNATIONAL JOURNAL OF ADVANCED MEDICINE : Volume-6 | Issue-4 | July-2022

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