Original Research Paper

Clinical Safety Of Zolindronic Acid In Osteoporosis: A Descriptive Cross Sectional Study

Abstract :

All bisphosphonates incuding zolindronic acid improve BMD in ostreoporosis and decrease risk of spine, hip and other non verteal fractures significantly. The purpose of this study was to assess safety of zolindronic acid in osteoporosis in kashmiri population. This was a descriptive cross sectional study conducted in teritiary care hospital of kashmir valley. 77 patients were enrolled in the study with documented osteoporosis who received 5 mg zolindronic acid infusion with adequate prior hydration. All pts were followed for immediate adverse effects following infusion. Mild symptoms did occur in the form of fever, arthralgias, myalgias, muscle cramps and nausea. Majority of the symptoms subsided within two to three days of infusion. Our observations conclude that zolindronic acid is very much safe and fairly tolerated drug in osteoporosis.

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