Research Paper

Correlation Of Serum Vegf Levels With Il-10 In Gastritis Patients H. Pylori And Non H. Pylori

Abstract :

The objective of this study was to determine the correlation of serum VEGF levels with IL-10 in gastritis patients H. pylori and Non H. pylori. The study was conducted with a cross sectional design of 60 H. pylori and Non H. pylori gastritis patients after undergoing gastroscopy, biopsy and CLO test, followed by examination of serum VEGF and IL-10 levels by ELISA method. Data were analyzed by SPSS version 22. The difference was significant if p < 0.05. The mean VEGF in the group with H. pylori was much higher with a mean of 580.65 while in the group with Non H. pylori only with a mean of 335.65 (p = 0,0001). The mean IL-10 level in the H. pylori group was 0.94 and in patients with Non H. pylori it was 0.58 (p = 0.04). There was a significantly higher increase in serum VEGF and IL-10 levels in H. pylori gastritis patients compared to Non H. pylori.

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