Original Research Paper

Study Of Right Ventricular Systolic Pressure In Severe Anaemia Pre And Post Transfusion

Abstract :

BACKGROUND: Anaemia affects more than third of the worlds population and contributes to increased morbidity, mortality and decreased quality of life. Global anaemia prevalence was 30% in women of reproductive age. Iron deficiency is one of the leading contributors to the burden of disease, and particularly affects children and reproductive age women. It is the most common nutritional deficiency in developed and developing regions of the world. Approximately 12% of adult men and 54% of adult women in India have iron deficiency.AIM: To study the right ventricular systolic pressure in severe anaemia pre and post transfusionMATERIALS AND METHODS: A Hospital-based prospective study was conducted in the Department of General Medicine, Dr PSIMS & RF hospital for six months. A total of 33 cases with severe anaemia cases were admitted to the hospital during this period were taken into the study.RESULTS: Among the selected patients, most patients were belonging to the age group of 41-50 years (27.3%). Most females were suffering from severe anaemia (72.7%). Male : female ratio was 0.37 :1. There was highly significant statistical difference in the subject distribution on the basis of venous hum (p value: 0.001). Most subjects were suffering from clinically severe anaemia, (57.6%). Most subjects in the group were iron deficient.(51.51%). There was a highly significant statistical difference in the subject distribution on the basis of right ventricular systolic pressure. (p value: 0.001). Majority of patients are with mild pulmonary hypertension (62.5%), followed by moderate hypertension (25%). Decrease in RVSP is observed in 90% of cases after PRBC transfusion. CONCLUSION: Severe anaemia leads to increase in LV muscular mass, left ventricular internal dimension which includes- systole, left ventricular internal dimension-diastole right ventricular systolic pressure, right ventricular internal dimension-systole, right ventricular internal dimension-diastole all suggestive of volume overload condition. All these changes are reversible after packed red blood cell transfusion.

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