Research Paper

Effect Of Intravenous Fluid Supplementation In Healthy Term Neonates With Non-hemolytic Hyperbilirubinemia

Abstract :

Objective: The objective of this study was to evaluate the effect of intravenous fluid supplementation in healthy term neonates with non-hemolytic hyperbilirubinemia receiving phototherapy. Study Design: Randomized controlled trial conducted in a tertiary level neonatal care unit of a teaching institute in Kota. Methods: A total of 100 healthy term neonates with non-hemolytic hyperbilirubinemia between 2nd to 14th day of life (total serum bilirubin [TSB] >15 mg/dL [256 mol/L] to <25 mg/dL [428 mol/L]) were randomized to two groups. Group I (case group, n=50) received 1/3rd the maintenance intravenous fluid in addition to eastfeeding and phototherapy. Group II (control group, n=50) received only eastfeeding and phototherapy. The duration of phototherapy was compared. Results: Both the groups were comparable with respect to mean birth weight, gestational age, gender, mode of delivery, age at admission, admission weight, percentage of weight loss at admission, and TSB at inclusion. There was a significant difference in the duration of phototherapy between the two groups (mean [standard deviation (SD)] Group I, 124.48(6.86)h and Group II, 168.67(7.63)h, p<0.05). Conclusion: Intravenous fluid supplementation in healthy eastfed term neonates with non-hemolytic hyperbilirubinemia significantly reduces the duration of phototherapy.

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