Research Paper

Evaluation Of Preemptive Intramuscular Ephedrine Vs Phenylephrine In Prevention Of Hypotension Induced By Spinal Anesthesia In Lower Segment Caesarean Section

Abstract :

Hypotension is the commonest side effect after giving spinal anaesthesia in Lower segment caesarean section. Many methods have been tried for prevention of hypotension. The present study was planned to compare effects of preemptive Phenyleprine and Ephedrine IM in the patients developing hypotension after spinal block during cesarean section. For this 90 pregnant females with single pregnancy, term gestation and aged between 18-45 years were selected on the basis of predefined criteria and then randomly divided into 3 groups having 30 patients each. In Group A Phenylephrine 4mg IM was given, in Group B Ephedrine 30mg IM was given whereas in Group C IM normal saline was given. In this study measurement of mean systolic and diastolic blood pressures, heart rate, was done at different interval of time along with presence of hypotension and nausea/ vomiting. Results were drawn as per statistical parameters. The fall in systolic blood pressure as well as mean blood pressure was found maximum in Group C, followed by Group B then Group A. There was statistically insignificant fall in diastolic blood pressure in Group A as well as Group B but it was statistically significant in Group C. There was no significant change in heart rate in both Groups A and C in any of the patients whereas there was a significant increase in heart rate in Group B. Maximum patients of hypotension and nausea/vomiting were seen in group C i.e. 70% and 53.3% respectively.

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